Dr. Daniel Rothfuss is an astrophysicist associated with the Project Blackstone. He is also very proficient with technology. Rothfuss is crippled, and bound to a wheelchair.
Upon his arrival at the Blackstone facility, Rothfuss was given clearence-level beta. He wondered what it would take to get to omega level.
He believed Adjutant 33-27_V3.1974 was too reserved, and figured she would open up to him as they got to know each other. He sarcastically commented on the quality of the tools provided by the Dominion.
Rothfuss provided several Blackstone staff including Red Quinton and Dr. Talen Ayers with devices that allowed them to communicate with each other without alerting Dominion security. His knowledge of the programming that serves as the base code for all Dominion systems allows him access to Blackstone's classified files.
When Dr. Ayers questions Dr. Rothfuss on his loyalty to the Dominion, he replied that he is loyal to humanity as a whole, and that the Dominion is right not to trust him. He then stated that after learning what their research was being used for, his goal was to destroy the project.
When Dr. Warren Held released a group of frenzied zerglings into the facility, Rothfuss was lead to safety by Lee Treicher, and his wheelchair was pushed by Pamela Foster. Rothfuss attempted to guide the scientists to the Daisy 8, the one transport off of the facility, but it was taken by Winlaleah Martine, who abandoned the scientists in the base. Eventually, when all the zerglings were dead, she had only one bullet left, which she decided to save for Held. Rothfuss followed the scientists to the sublevels where Held was hiding. They reached the sublevels, where they found that Dr. Held was already dead, killed by the last surviving protoss prisoner.
Rothfuss and the other survivors were rescued by a Dominion force led by Valerian Mengsk, now emperor of the Terran Dominion. He offered them a place on the Brin, a science vessel on which Project Blackstone would be continued.