Nova embarks on a mission to uncover the frightening truth behind Project: Shadow Blade - this conspiracy will cause her to question her own identity while embroiled in a struggle between the Terran Dominion and the rebel Koprulu Liberation Front.
The opening video of StarCraft: Ghost shows a group of Terran Dominion Marines (and a few Firebats) assaulting a Zerg-infested "Vespene" refinery (actually a terrazine refinery) on Mar Sara. Captain Bok leads the group, but is incompetent; his forces promptly fall into a Zerg ambush. He pleads for reinforcements, which arrive in the form of the Dropships, one of which is carrying Nova. Two of the dropships are shot down by Mutalisks but the third safely lands, disgorging the black ops unit and Nova.
According to previews of the game, Nova's first mission involves a raid on a Supply Depot on Abaddon, where members of the Koprulu Liberation Front hold a Terran Grizzly they have stolen from the Dominion, along with a captured engineer. Nova is ordered to retrieve the engineer and the Grizzly, but the engineer is murdered before she can save them.